Many people are under the misconception that Botox and facial fillers such as Restylane, Juvaderm, Radiesse have the same action or purpose. This is a short note to set the record straight. Botox is a neuromuscular inhibitor that prevents motor nerves from exerting action on muscle, thus preventing contraction which in turn prevents wrinkling. Fillers, on the other hand, provide mass to concavities to elevate the furrows and thus make them less deep. In certain situations the end result may be the same, such as forehead frown lines, but in other areas such as the deep nasal lines (naso-labial folds) only long lasting fillers such as Radiesse will help. Remember that all of these treatments are temporizing measures, before one is ready to commit to more invasive but more permanent solutions.